ETHYL (P-FLUOROBENZOYL)ACETATE
Ethyl 3-(4-fluorophenyl)-3-oxopropanoate
CAS: 1999-00-4
Molecular Formula: C11H11FO3
ETHYL (P-FLUOROBENZOYL)ACETATE - Names and Identifiers
ETHYL (P-FLUOROBENZOYL)ACETATE - Physico-chemical Properties
| Molecular Formula | C11H11FO3 |
| Molar Mass | 210.2 |
| Density | 1.174g/mLat 25°C(lit.) |
| Melting Point | 117-120℃ |
| Boling Point | 117-120°C(lit.) |
| Flash Point | >230°F |
| Vapor Presure | 0mmHg at 25°C |
| Appearance | clear liquid |
| Specific Gravity | 1.19 |
| Color | Colorless to Almost colorless |
| pKa | 9.82±0.25(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | n20/D 1.5040(lit.) |
| Physical and Chemical Properties | WGK Germany:3 |
ETHYL (P-FLUOROBENZOYL)ACETATE - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Safety Description | 24/25 - Avoid contact with skin and eyes. |
| WGK Germany | 3 |
| HS Code | 29183000 |
| Hazard Note | Irritant |
ETHYL (P-FLUOROBENZOYL)ACETATE - Introduction
Ethyl 3-(4-fluorophenyl)-3-oxopropanoate, with the chemical formula C9H9FO2, is an organic compound. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is a colorless to light yellow liquid.
-Solubility: It dissolves well in organic solvents such as ethanol, ether and chloroform.
-Melting point and boiling point: Its melting point is about -18 ° C, and its boiling point is 199-201 ° C.
-Toxicity: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate may have certain toxicity and need to be used carefully.
Use:
-Chemical reagent: It is commonly used as an acylation reagent and a fluorine atom introduction reagent in organic synthesis reactions.
-Pesticide intermediate: In the agricultural field, it can be used as a synthetic precursor for certain pesticides and herbicides.
-Drug synthesis: It can also be used as a synthetic intermediate for certain drugs, such as certain anti-inflammatory drugs.
Method:
The preparation method of Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is usually obtained by reacting 4-fluorobenzoic acid and Ethyl acetoacetate under acidic conditions. The reaction requires appropriate safety measures, such as wearing protective gloves and glasses, and is carried out in a well-ventilated laboratory.
Safety Information:
- Ethyl 3-(4-fluorophenyl)-3-oxopropanoate may be toxic and should be avoided by inhalation and skin contact.
-Wear appropriate personal protective equipment, such as protective gloves and glasses, during use and handling.
-Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
-When storing, it should be placed in a cool, dry, well-ventilated place, away from fire and flammable substances.
-When handling the compound, correct handling and disposal methods should be followed to comply with local environmental and safety regulations.
Nature:
-Appearance: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is a colorless to light yellow liquid.
-Solubility: It dissolves well in organic solvents such as ethanol, ether and chloroform.
-Melting point and boiling point: Its melting point is about -18 ° C, and its boiling point is 199-201 ° C.
-Toxicity: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate may have certain toxicity and need to be used carefully.
Use:
-Chemical reagent: It is commonly used as an acylation reagent and a fluorine atom introduction reagent in organic synthesis reactions.
-Pesticide intermediate: In the agricultural field, it can be used as a synthetic precursor for certain pesticides and herbicides.
-Drug synthesis: It can also be used as a synthetic intermediate for certain drugs, such as certain anti-inflammatory drugs.
Method:
The preparation method of Ethyl 3-(4-fluorophenyl)-3-oxopropanoate is usually obtained by reacting 4-fluorobenzoic acid and Ethyl acetoacetate under acidic conditions. The reaction requires appropriate safety measures, such as wearing protective gloves and glasses, and is carried out in a well-ventilated laboratory.
Safety Information:
- Ethyl 3-(4-fluorophenyl)-3-oxopropanoate may be toxic and should be avoided by inhalation and skin contact.
-Wear appropriate personal protective equipment, such as protective gloves and glasses, during use and handling.
-Avoid contact with strong oxidants and strong acids to avoid dangerous reactions.
-When storing, it should be placed in a cool, dry, well-ventilated place, away from fire and flammable substances.
-When handling the compound, correct handling and disposal methods should be followed to comply with local environmental and safety regulations.
Last Update：2024-04-09 02:00:44
Supplier List
Featured ProductsSpot supply
Product Name: Ethyl (4-Fluorobenzoyl)acetate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate Request for quotationCAS: 1999-00-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Ethyl (4-Fluorobenzoyl)acetate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
Featured ProductsSpot supply
Product Name: Ethyl (4-Fluorobenzoyl)acetate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: +86-18821248368
Email: Int06@meryer.com
Mobile: +86-18821248368
QQ: 495145328
WhatsApp: +86-18821248368
Spot supply
Product Name: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate Request for quotationCAS: 1999-00-4
Tel: 400-968-2212
Email: 3623107365@qq.com
Mobile: 18916960931
QQ: 3623107365
Wechat: 18916960931
Spot supply
Product Name: Ethyl (4-Fluorobenzoyl)acetate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: +86-400-900-4166
Email: product@acmec-e.com
Mobile: +86-18621343501
QQ: 2881950922
Wechat: 18621343501
WhatsApp: +86-18621343501
Spot supply
Product Name: Ethyl 3-(4-fluorophenyl)-3-oxopropanoate Visit Supplier Webpage Request for quotationCAS: 1999-00-4
Tel: 609-228-6898
Email: sales@medchemexpress.com
tech@medchemexpress.com
Mobile: 609-228-6898
View History